In the afternoon I had to force quit Thunderbird on my Mac Mini running macOS Mojave. When I tried to restart Thunderbird I was greeted with the following message:
A copy of Thunderbird is already open. Only one copy of Thunderbird can be open at a time.
The fix for this is easy: deleting the lock file that Thunderbird has left behind when I killed it.
First, I opened the terminal and changed into Thunderbird's Profiles directory:
Next, I used
ls -1 to find the name of my default profile directory,
I changed into this directory and deleted the file named
cd jt1wxigb.default/ rm .parentlock
And finally I restarted Thunderbird, successfully this time.